JWH-018 is more robust than THC or tetrahydrocannabinol, The real key Lively ingredient in cannabis. A small dose is ample to induce an intoxicating outcome. JWH-018 binds the CB1 receptor four moments a lot more tightly along with the CB2 receptor ten periods a lot more tightly than THC.Psychosis – The extended use of synthetic cannabinoids may